Notes
Writings about various topics and discussion worthy proteins
Factor C
horseshoe crab protein that senses endotoxins
Created on
The protein, Factor C , found in horseshoe crabs, is responsible for triggering a coagulation cascade in response to endotoxin. The test for bacterial endotoxin uses blood drawn from horseshoe crabs, is a sensitive, reproducible and simple assay to measure endotoxin concentrations.
Genetic engineering has been used to develop generation reagents for endotoxin quantification that do not rely on a horseshoe crab itself [1].
Companies
- Sothic Bio is a company trying to synthetically synthesize the components of LAL.
Discussions
References
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