Careers at Serotiny

Senior Scientist / Principal Scientist – Cell Therapy

SOUTH SAN FRANCISCO, CA, FULL-TIME

Description

Serotiny invents multi-domain proteins for gene and cell therapies including genome editors, and chimeric antigen receptors (CARs). Our infrastructure is a design/build/test loop that couples a finely tuned software architecture with wet-lab mammalian synthetic biology to engineer and characterize massive libraries of candidates. These novel synthetic proteins are central to cutting edge therapeutics, providing enhanced efficacy and safety through advanced control methods and engineered functionalities.

Serotiny is looking for a Sr. Research Associate / Scientist who is excited to work closely with a team of immunologists and molecular biologists to build and deploy Serotiny's high-throughput C&GT methods.

Role

  • Lead from the bench in the design, manufacture and functional screening of novel CAR constructs discovered using Serotiny’s high-throughput platform
  • Train and guide the professional development of junior staff
  • Maintain outstanding electronic lab notebook records
  • Collaborate with software engineers, bioinformaticians and platform engineers to develop protein design and evaluation methodologies
  • Assist R&D leadership on constructing non-clinical development strategies, from discovery to early clinical development

Qualifications

  • Degree in immunology, cell biology, molecular biology, biotechnology or related area
    • Sr. Scientist: BSc. with >8 years of experience, or MSc. with >3 year of experience, or PhD. with >2 years of industry or other relevant experience
    • Principal Scientist: BSc. with >10 years of experience, or MSc. with >5 years of experience, or PhD. with >4 years of industry or other relevant experience
  • Hands-on experience with synthetic proteins relevant to immunotherapies (ie, CARs)
  • Proven experience working as project leader of studies that have led to IND enabling packages is a plus
  • Skilled in Cell Therapy workflows: Primary cell isolation, activation, transduction, and cryopreservation, as well as, functional in vitro assays for characterization of T cell function (cytotoxicity, proliferation, cytokine release)
  • Experience with immunostaining methods, flow cytometry, FACS, ELISA
  • Excellent organizational skills, detail oriented and an ability to prioritize effectively to deliver results within reasonably established timelines
  • Outstanding verbal and written communication skills
  • Flexibility to work in a fast-paced startup environment and able to adjust workload based upon changing priorities
  • Candidates must be authorized to work in the US

Perks

  • Full health benefits
  • Budget to host and attend biology conferences/meetups
  • Opportunities to research and publish cutting edge synthetic biology
  • Opportunity to invent new proteins and design methodologies


We're always looking for talented people interested in developing the next generation of cell therapies.

Please reach out to us at jobs_lab@serotiny.com