About Serotiny

Inspired by life – Serotiny digitally encodes nature’s features and functions into a biologically aware API for the high-throughput, rational design of multi-domain synthetic proteins.

By coupling state-of-the-art mammalian synthetic biology and a finely-tuned software architecture, Serotiny aims to embrace one of the greatest opportunities of the 21st century to improve people’s lives. Serotiny designs custom proteins with cutting edge capabilities including treatment of cancers and genetic disorders. We partner with leaders in the life sciences to give proteins wholly new functions for more effective, safer, and customized therapies.

With support from world-class investors including Nanodimension and 8VC, Serotiny is proud to build a cross-disciplinary team of passionate individuals with varied experiences.

Mammalian Synthetic Biology - Protein Engineer
San Francisco, CA, Full Time


This person will lead Serotiny’s capabilities to engineer novel synthetic proteins and will collaborate with software developers to deploy creative protein engineering methodologies.

The infrastructure is part of a high-throughput design/build/test loop that couples a finely tuned software architecture with wet-lab mammalian synthetic biology. Serotiny is looking for our first protein engineer who is excited to utilize Serotiny’s novel software architecture to build and refine proteins for immunology and gene editing.


  • Collaborate with synthetic biologists to design and evaluate novel protein constructs
  • Efficiently identify and analyze constructs used in scientific literature
  • Design experiments to test the functionality of novel proteins in mammalian systems in high-throughput
  • Collaborate with software engineers to develop the design and analysis methodologies
  • Manage a synthetic biology lab


  • Ph.D. in molecular biology or Ph.D. with equivalent experience in synthetic biology
  • Direct experience with designing novel multi-domain proteins (Optogenetic, split, chimeric, tagged, etc.)
  • Expertise in mammalian synthetic biology
  • Desire to manage a lab
  • Flexibility and desire to work at the early stages of a startup


  • Full health benefits
  • Budget to host and attend biology conferences/meetups
  • Opportunities to research and publish cutting edge synthetic biology
  • Opportunity to invent new proteins and design methodologies